For years, OpenCRAVAT has answered a deceptively simple question, what is known about this variant? by letting you assemble exactly…
Blog Post
Announcing two new gene level annotators from the Network of Cancer Genes & Healthy Drivers. The Network of Cancer Genes…
Due to licensing issues, the COSMIC and Cancer Gene Census annotators will no longer be available on the OpenCRAVAT store….
We are pleased to announce the release of the OpenCRAVAT MCP server, a new service that makes OpenCRAVAT’s variant annotation…
Visit the new public OpenCRAVAT Store! OpenCRAVAT utilizes over 300 modules to interpret and annotate variant information. Converters read in…
Despite the massive strides made in genomic science and AI over the last two decades, no single variant annotation tool…
Variant interpretation is central to genomic medicine, but one of its most debated areas is how to use computational evidence….
Moez Dawood, an MD/PhD student at Baylor College of Medicine, has recently developed the AllofUs 250k annotator for OpenCRAVAT, a…
At ACMG 2025, Dr. Moez Dawood announced a groundbreaking initiative: the global democratization of deidentified allele count and frequency data…
As a part of our ongoing effort to update our variant effect predictors with calibration for ACMG/AMP classifications, we have…

